WNK1 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Enriched expression of this gene

Enriched expression of this gene in embryonic mouse brain suggests that this gene may play a role in nervous system development

The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks

Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p

containing 7 cadherin domains

Pseudogenes corresponding to this gene are found on chromosomes 8p

WNK1 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Enriched expression of this geneWNK1 encodes a member of the WNK subfamily of serine threonine protein kinases. The serine threonine protein kinase WNK1 may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full length