STEAP2 Polyclonal Antibody, 50ul Dry Bath osteoblasts

osteoblasts

Mutations in this gene are a cause of Native American myopathy

The functional enzyme is thought to be a homodimer which uses FAD as a cofactor

May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage

and ionic requirements

STEAP2 Polyclonal Antibody, 50ul Dry Bath osteoblastsSTEAP2 is a member of the STEAP family and encodes a multi pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression.