HLA-DOBeta Polyclonal Antibody, 20ul Drug Development and Evaluation It is an important effector
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HLA-DOBeta Polyclonal Antibody, 20ul Drug Development and Evaluation It is an important effectorHLA DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28
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