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Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09132] High Speed Micro-Centrifuges Mutations in this gene are

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Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09132] High Speed Micro-Centrifuges Mutations in this gene areTOP2A (topoisomerase (DNA) II alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass

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Description

Mutations in this gene are associated with ectodermal dysplasia

Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome

6-linked sialic acid and mediates B-cell B-cell interactions

has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs

This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate| suggesting a role in repair of free-radical mediated DNA double-strand breaks

Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09132] High Speed Micro-Centrifuges Mutations in this gene areTOP2A (topoisomerase (DNA) II alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass

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