Mcl-1 Polyclonal Antibody, 20ul[BT-AP05274] Drug Development and Evaluation Alternative splicing of this gene

Alternative splicing of this gene generates two transcript variants diverging in the 3' region

APP (amyloid beta precursor protein) encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides

PES express has faster filtration and lower clogging rate

It is now widely accepted that KSR1 functions as a scaffold that binds MEK1/2 and 14-3-3 protein constitutively and binds ERK1/2 in a Ras activation-dependent manner

CD69 encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors

Mcl-1 Polyclonal Antibody, 20ul[BT-AP05274] Drug Development and Evaluation Alternative splicing of this geneMCL1 encodes an anti apoptotic protein, which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.