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VMAT2 Polyclonal Antibody, 50ul Cell Separation and Collection The protein functions as a

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VMAT2 Polyclonal Antibody, 50ul Cell Separation and Collection The protein functions as aThe vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al.,

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Description

The protein functions as a guanine nucleotide exchange for RAB5B and RAB31

cell-to-cell signaling

depending on the absence or presence

Mutations in SLC22A18 have been found in Wilms' tumor and lung cancer

A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient

VMAT2 Polyclonal Antibody, 50ul Cell Separation and Collection The protein functions as aThe vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al.,

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