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GLP1R Polyclonal Antibody, 20ul Immuno Plates Runt-related transcription factor 1 (RUNX1)

SKU: 92777287052

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GLP1R Polyclonal Antibody, 20ul Immuno Plates Runt-related transcription factor 1 (RUNX1)This gene encodes a 7 transmembrane protein that functions as a receptor for glucagon like peptide 1 (GLP 1) hormone, which stimulates glucose induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP 1 and GLP 1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene

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Description

Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) is a protein that in humans is encoded by the RUNX1 gene

Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported

Cyclin dependent kinase inhibitor 2C has been shown to interact with CDK4 or CDK6

Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms

PTGDR (prostaglandin D2 receptor) encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily

GLP1R Polyclonal Antibody, 20ul Immuno Plates Runt-related transcription factor 1 (RUNX1)This gene encodes a 7 transmembrane protein that functions as a receptor for glucagon like peptide 1 (GLP 1) hormone, which stimulates glucose induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP 1 and GLP 1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene

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