Histone H3(Phospho Thr32) Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Disruption of this gene by

Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas

as well as the related connective tissue disorder

Mutations in this gene have been associated with venous thromboembolism and myocardial infarction

The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease

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Histone H3(Phospho Thr32) Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Disruption of this gene byHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin