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ABI3 Polyclonal Antibody, 20ul Low-speed Centrifuges miscellaneous:Knockdown significantly reduces the adhesion

SKU: 9261377334

4.6
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ABI3 Polyclonal Antibody, 20ul Low-speed Centrifuges miscellaneous:Knockdown significantly reduces the adhesionThis gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain proline rich region and Src homology 3 (SH3) domain and are components of the Abi WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21 activated kinase. Alternative splicing

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Description

miscellaneous:Knockdown significantly reduces the adhesion of cancer cells to lung microvascular endothelial cells and the reciprocal effect is observed following overexpression

Mutations in this gene have been associated with chronic granulomatous disease

Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene

Leucine-rich repeat-containing G-protein coupled receptor 6 is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding

including Dbf4

ABI3 Polyclonal Antibody, 20ul Low-speed Centrifuges miscellaneous:Knockdown significantly reduces the adhesionThis gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain proline rich region and Src homology 3 (SH3) domain and are components of the Abi WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21 activated kinase. Alternative splicing

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