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Tie-1 Polyclonal Antibody, 50ul Centrifuges This gene is a candidate

SKU: 92187034037

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PLN162.00 PLN195.00

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Tie-1 Polyclonal Antibody, 50ul Centrifuges This gene is a candidateTIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1) encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth

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Description

This gene is a candidate for the ovarian tumor suppressor gene

Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus| multiple sclerosis and rheumatoid arthritis

TRAF proteins associate with

C1Q and collagen domain containing) with similarity to collagens X and VIII and complement factor C1q

The encoded protein is expressed in endothelial cells

Tie-1 Polyclonal Antibody, 50ul Centrifuges This gene is a candidateTIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1) encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth

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