Human Receptor-type Tyrosine-protein Phosphatase Eta, PTPRJ ELISA Kit, 96T Vessels Also involved in Golgi disassembly

Also involved in Golgi disassembly during the cell cycle: part of a MEK1/MAP2K1-dependent pathway that induces Golgi fragmentation during mitosis by mediating phosphorylation of VRK1

Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID)| in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins| whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia

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the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins

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Human Receptor-type Tyrosine-protein Phosphatase Eta, PTPRJ ELISA Kit, 96T Vessels Also involved in Golgi disassembly