Stat3 Polyclonal Antibody, 20ul[BT-AP01663] Subcellular Fractions and age-related macular degeneration type

and age-related macular degeneration type 3 (ARMD3)

The protein shares significant amino acid similarity with S

MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins

This protein and VP16 both bind to the same site on host cell factor C1

|tissue specificity:Expressed principally in liver

Stat3 Polyclonal Antibody, 20ul[BT-AP01663] Subcellular Fractions and age-related macular degeneration typeThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.