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ATL1 Polyclonal Antibody, 50ul Low-speed Centrifuges Similar to STAM| this protein

SKU: 9167631323

4.4
USD162.00 USD187.00

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ATL1 Polyclonal Antibody, 50ul Low-speed Centrifuges Similar to STAM| this proteinThis gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants

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Description

Similar to STAM| this protein acts downstream of JAK kinases| and is phosphorylated in response to cytokine stimulation

This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription

This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver

although its specific function is unknown

The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction

ATL1 Polyclonal Antibody, 50ul Low-speed Centrifuges Similar to STAM| this proteinThis gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants

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