Raf-1(Phospho Ser259) Polyclonal Antibody, 100ul Reagent Reservoirs LIFR encodes leukemia inhibitory factor

LIFR encodes leukemia inhibitory factor receptor alpha that belongs to the type I cytokine receptor family

Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor

The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning

It is a candidate gene encoding tumor antigens

called coated vesicles and coated pits

Raf-1(Phospho Ser259) Polyclonal Antibody, 100ul Reagent Reservoirs LIFR encodes leukemia inhibitory factorThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.