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Human Gasdermin D, GSDMD ELISA Kit, 96T Microplate Mixer It interacts preferentially with the

SKU: 90946475631

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Human Gasdermin D, GSDMD ELISA Kit, 96T Microplate Mixer It interacts preferentially with the[Gasdermin D]: Precursor of a pore forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed: 26375003, PubMed: 26375259, PubMed: 27281216). This form constitutes the precursor of the pore forming protein: upon cleavage, the released N terminal moiety (Gasdermin D, N terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed: 26375003, PubMed: 26375259, PubMed: 27281216). [Gasdermin D,

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Description

It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B

which constitute the regulatory and active subunit of TGF-beta-1

May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases

This protein resembles yeast Prp16 more closely than other DEAD/H family members

it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity)

Human Gasdermin D, GSDMD ELISA Kit, 96T Microplate Mixer It interacts preferentially with the[Gasdermin D]: Precursor of a pore forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed: 26375003, PubMed: 26375259, PubMed: 27281216). This form constitutes the precursor of the pore forming protein: upon cleavage, the released N terminal moiety (Gasdermin D, N terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed: 26375003, PubMed: 26375259, PubMed: 27281216). [Gasdermin D,

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