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p18 Polyclonal Antibody, 50ul Measuring Instruments Mutations in this gene are

SKU: 90873008505

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p18 Polyclonal Antibody, 50ul Measuring Instruments Mutations in this gene areCyclin dependent kinase inhibitor 2C encoded by CDKN2C is a member of the INK4 family of cyclin dependent kinase inhibitors. Cyclin dependent kinase inhibitor 2C has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of CDKN2C was shown to suppress the growth of human cells in a manner that appears to correlate

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Description

Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy

This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined

This pseudogene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7

This PTP was found to be activated by polyphosphoinositide

The protein can efficiently bind the NGFI-B Response Element (NBRE)

p18 Polyclonal Antibody, 50ul Measuring Instruments Mutations in this gene areCyclin dependent kinase inhibitor 2C encoded by CDKN2C is a member of the INK4 family of cyclin dependent kinase inhibitors. Cyclin dependent kinase inhibitor 2C has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of CDKN2C was shown to suppress the growth of human cells in a manner that appears to correlate

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