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UBE1L Polyclonal Antibody, 50ul Drying & Desiccation CLASP1 is involved in the

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UBE1L Polyclonal Antibody, 50ul Drying & Desiccation CLASP1 is involved in theThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes, or E1s, ubiquitin conjugating enzymes, or E2s, and ubiquitin protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin activating enzyme family. The encoded enzyme is a retinoid target that triggers

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Description

CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al

In addition| this protein interacts with and phosphorylates BRCA1| allowing BRCA1 to restore survival after DNA damage

This protein and ATM share similarity with Schizosaccharomyces pombe rad3| a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage

This caspase is able to cleave and activate its own precursor protein

NRP2 encodes a member of the neuropilin family of receptor proteins

UBE1L Polyclonal Antibody, 50ul Drying & Desiccation CLASP1 is involved in theThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes, or E1s, ubiquitin conjugating enzymes, or E2s, and ubiquitin protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin activating enzyme family. The encoded enzyme is a retinoid target that triggers

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