TIEG-1/2 Polyclonal Antibody, 50ul Site-directed Mutagenesis and mutations in MYOC have

and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma

An important paralog of this gene is ACOT2

TP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development

but they differ significantly over the 3' untranslated regions

Several alternatively spliced transcript variants have been identified

TIEG-1/2 Polyclonal Antibody, 50ul Site-directed Mutagenesis and mutations in MYOC haveKLF10 (Kruppel like factor 10) encodes a member of a family of proteins that feature C2H2 type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.