GLCNE Polyclonal Antibody, 20ul Polyclonal Antibodies With N1-Me-pUTP and CAP GAG

With N1-Me-pUTP and CAP GAG

a ubiquitous protein kinase which regulates metabolic pathways

Six alternatively spliced transcript variants encoding different isoforms have been reported

and has been linked to primary microcephaly and Alzheimer's disease

The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth

GLCNE Polyclonal Antibody, 20ul Polyclonal Antibodies With N1-Me-pUTP and CAP GAGThe glucosamine (UDP N acetyl) 2 epimerase N acetylmannosamine kinase encoded by GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction.