Histone H2A.X(Phospho Ser139) Polyclonal Antibody, 100ul[BT-AP09928] Lysosome SP100 (SP100 nuclear antigen) encodes

SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies

SCF(BTRC) directs ubiquitination of NFKBIB

Detected at high levels in hipppocampus

Mutations in C9 cause component C9 deficiency

and as a heterodimer with a similar brain isozyme in heart

Histone H2A.X(Phospho Ser139) Polyclonal Antibody, 100ul[BT-AP09928] Lysosome SP100 (SP100 nuclear antigen) encodesHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This