SHIP2(Phospho-Tyr1135) Rabbit Polyclonal Antibody, 20ul Lentiviral Packaging NF-kappa-B moves to the nucleus

NF-kappa-B moves to the nucleus and activates transcription of specific genes

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

Mutations in ITPR1 cause spinocerebellar ataxia type 15

Mutations in this gene cause primary bile acid malabsorption (PBAM)

This gene encodes a secreted

SHIP2(Phospho-Tyr1135) Rabbit Polyclonal Antibody, 20ul Lentiviral Packaging NF-kappa-B moves to the nucleusThe protein encoded by this gene is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.