RASEF Polyclonal Antibody, 100ul Adeno-associated Virus Packaging The CDK8 subcomplex modulates Mediator-polymerase

The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates

Mutations in this gene have been associated with bone marrow failure syndrome 2

subcellular location:Colocalizes with nuclear pore complex protein NUP62

This highly conserved protein family is found in both plants and mammals| and this protein is 99% identical to the mouse| rat and sheep orthologs

This protein contains a PHD-finger

RASEF Polyclonal Antibody, 100ul Adeno-associated Virus Packaging The CDK8 subcomplex modulates Mediator-polymeraseThis gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N terminal EF hand domain, a coiled coil motif and a C terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene.