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Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation PHACTR4 (phosphatase and actin regulator

SKU: 89388664706

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Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation PHACTR4 (phosphatase and actin regulatorThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

PHACTR4 (phosphatase and actin regulator 4) encodes a member of the phosphatase and actin regulator (PHACTR) family

Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al

which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377

Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain

NBL1 product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins

Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation PHACTR4 (phosphatase and actin regulatorThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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