PAK1/2(Phospho-Ser199/204) Rabbit Polyclonal Antibody, 20ul Liquid Handling LILRA2 is located in a

LILRA2 is located in a cluster of related genes on chromosome 19 and there is a pseudogene for LILRA2 on chromosome 3

It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors

The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus

TLN1 encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts

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PAK1/2(Phospho-Ser199/204) Rabbit Polyclonal Antibody, 20ul Liquid Handling LILRA2 is located in aThis gene encodes a family member of serine threonine p21 activating kinases known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.