NOSTN Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis It is mitogenic for fibroblasts

It is mitogenic for fibroblasts and smooth muscle but not endothelial cells

Serine/threonine-protein kinase PLK2 encoded by PLK2 is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division

vesicular stomatitis virus (VSV)

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)

The physiological function has not been determined but it is known that the protein binds heme

NOSTN Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis It is mitogenic for fibroblastsNitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission inflammatory response and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production endothelial NO synthase (ENOS; MIM 163729) and triggers the translocation of ENOS from the plasma membrane to vesicle like subcellular structures thereby attenuating ENOS dependent NO production.