CD48 Polyclonal Antibody, 100ul General Lab Use Probable E3 ubiquitin-protein ligase which

Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster

SCF complexes| formed by SKP1 (MIM 601434)| cullin (see CUL1

an important regulator of blood pressure and electrolyte balance

An important paralog of this gene is COL6A1

CD48 Polyclonal Antibody, 100ul General Lab Use Probable E3 ubiquitin-protein ligase whichCD48 encodes a member of the CD2 subfamily of immunoglobulin like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The CD48 antigen is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI