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ARBK1 Polyclonal Antibody, 50ul Primary Antibodies Two transcript variants encoding different

SKU: 88389998259

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ARBK1 Polyclonal Antibody, 50ul Primary Antibodies Two transcript variants encoding differentThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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Description

Two transcript variants encoding different isoforms have been found for HSP90AA1

It possesses at least two conserved domains that could be important for its function

thus is potentially associated with higher risk of breast cancer

and brain tumors

Multiple alternatively spliced transcript variants have been found for PDK1

ARBK1 Polyclonal Antibody, 50ul Primary Antibodies Two transcript variants encoding differentThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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