Insulin R Polyclonal Antibody, 100ul[BT-AP04564] Gene Synthesis is expressed primarily in the

is expressed primarily in the brain

A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation

The encoded protein is expressed in lens fiber cells after differentiation has begun

The protein localizes to actin-rich structures including membrane ruffles| microvilli| and filopodia

including intracellular signaling

Insulin R Polyclonal Antibody, 100ul[BT-AP04564] Gene Synthesis is expressed primarily in theINSR encodes a member of the receptor tyrosine kinase family of proteins. Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited