ERCC2 Polyclonal Antibody, 20ul PCR Series The encoded proteins binds to

The encoded proteins binds to its own promoter as well as to that of several target genes

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain

The PDH complex contains three catalytic subunits| E1| E2| and E3| two regulatory subunits| E1 kinase and E1 phosphatase| and a non-catalytic subunit| E3 binding protein (E3BP)

and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis

The encoded type 2 transmembrane protein may function as a cell surface antigen

ERCC2 Polyclonal Antibody, 20ul PCR Series The encoded proteins binds toThe nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2 TFIIH complex. The gene product has ATP dependent DNA helicase activity and belongs to the RAD3 XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer prone syndrome