ErbB-3(Phospho Tyr1328) Polyclonal Antibody, 50ul Cell Culture Nonsense mutations have been reported

Nonsense mutations have been reported to result in cytochrome c oxidase deficiency

leading to a CBL dependent degradation of signaling proteins

this protein can undergo autophosphorylation

The corticotropin releasing hormone receptor 2 encoded by CRHR2 belongs to the G-protein coupled receptor 2 family

The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family

ErbB-3(Phospho Tyr1328) Polyclonal Antibody, 50ul Cell Culture Nonsense mutations have been reportedThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the