TRAP220 Polyclonal Antibody, 100ul[BT-AP09180] Deep Well Plates DR3 was thought to be

DR3 was thought to be a receptor for TWEAK

Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3

Involved in decreased protein synthesis in atrophying skeletal muscle

and its gene mutation and increased expression may be associated with human cancer

Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides

TRAP220 Polyclonal Antibody, 100ul[BT-AP09180] Deep Well Plates DR3 was thought to beThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by MED1 (mediator complex subunit 1) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.