NF-YC Polyclonal Antibody, 100ul Sealing Film which causes progressive bone overgrowth

which causes progressive bone overgrowth

and is therefore a potential candidate gene for this disorder

Alternatively spliced transcript variants encoding multiple isoforms have been observed for MED27

The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells

Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome

NF-YC Polyclonal Antibody, 100ul Sealing Film which causes progressive bone overgrowthNFYC encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone like motif. Multiple transcript variants