E2F-6 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Mutations in this gene cause

Mutations in this gene cause hyperlipoproteinemia type IB

with the exception of the B-cell expressed SIGLEC6 (MIM 604405)

This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family

T-cell receptor enhancers and GM-CSF promoters

The encoded protein may be involved in endocytic sorting

E2F-6 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Mutations in this gene causeE2F6 encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. E2F transcription factor 6 encoded by E2F6 lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene