MTHFR Polyclonal Antibody, 50ul Custom DNA Oligos Mutations in the repeat region

Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit

VE-cadherin is a classical cadherin molecule

The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32

This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene

MTHFR Polyclonal Antibody, 50ul Custom DNA Oligos Mutations in the repeat regionMethylenetetrahydrofolate reductase encoded by MTHFR catalyzes the conversion of 5,10 methylenetetrahydrofolate to 5 methyltetrahydrofolate, a co substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.