HIBADH Polyclonal Antibody, 100ul Erlenmeyer Flasks SOCS family members are cytokine-inducible

SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway)

This gene is included in the surfeit gene cluster

Several transcript variants are formed through the use of alternative translation initiation sites and promoters

|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4

tissue specificity:Specifically expressed in endothelial cells

HIBADH Polyclonal Antibody, 100ul Erlenmeyer Flasks SOCS family members are cytokine-inducibleHIBADH encodes a mitochondrial 3 hydroxyisobutyrate dehydrogenase enzyme. The 3 hydroxyisobutyrate dehydrogenase plays a critical role in the catabolism of L valine by catalyzing the oxidation of 3 hydroxyisobutyrate to methylmalonate semialdehyde.