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PDK1(Phospho Ser241) Polyclonal Antibody, 100ul Microbial Genome Editing NFAT proteins are activated by

SKU: 86959713778

4.9
EUR123.75 EUR146.75

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PDK1(Phospho Ser241) Polyclonal Antibody, 100ul Microbial Genome Editing NFAT proteins are activated byCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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Description

NFAT proteins are activated by the calmodulin-dependent phosphatase| calcineurin

They seem to be equally abundant

An important paralog of this gene is HAP1

which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS)

RBM5 is located within the tumor suppressor region 3p21

PDK1(Phospho Ser241) Polyclonal Antibody, 100ul Microbial Genome Editing NFAT proteins are activated byCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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