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p53 (Acetyl Lys381) Polyclonal Antibody, 100ul Biomatrix It appears to function as

SKU: 86836504653

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p53 (Acetyl Lys381) Polyclonal Antibody, 100ul Biomatrix It appears to function asTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization

The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids

such as colon

which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival

GO annotations related to this gene include DNA-directed RNA polymerase activity and RNA polymerase I transcription factor binding

p53 (Acetyl Lys381) Polyclonal Antibody, 100ul Biomatrix It appears to function asTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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