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TRAP240 Polyclonal Antibody, 100ul[BT-AP09183] Sealing Film and this protein is 100%

SKU: 86822008185

4.6
USD108.00 USD147.00

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TRAP240 Polyclonal Antibody, 100ul[BT-AP09183] Sealing Film and this protein is 100%MED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.

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Description

and this protein is 100% identical to the mouse ortholog

retaining only two of four cysteines conserved in other chemokines

It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors

liver kidney and Ewing tumor cell lines

Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia

TRAP240 Polyclonal Antibody, 100ul[BT-AP09183] Sealing Film and this protein is 100%MED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.

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