PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection Diseases associated with SUPT3H include

Diseases associated with SUPT3H include blastic plasmacytoid dendritic cell

subcellular location:Associates with chromatin

including regulation of iron homeostasis

Mutations in SMARCA4 cause rhabdoid tumor predisposition syndrome type 2

Mapped to a previously identified cluster of cadherin genes on chromosome 16q22

PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection Diseases associated with SUPT3H includePEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.