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ATE1 Polyclonal Antibody, 100ul Cell fragmentation and collection Chromosomal aberrations involving this gene

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ATE1 Polyclonal Antibody, 100ul Cell fragmentation and collection Chromosomal aberrations involving this geneThis gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N terminal aspartate or glutamate residues. Conjugation of arginine to the N terminal aspartate or glutamate targets proteins for ubiquitin dependent degradation. Alternative splicing results in multiple transcript variants.

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Description

Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome

This gene is classified as a pseudogene because a splice donor in the 3' UTR has changed compared to other family members| rendering the transcript a candidate for nonsense-mediated mRNA decay (NMD)

The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu

CD2 molecule encoded by CD2 is a surface antigen found on all peripheral blood T-cells

and patients homozygous for a variant haplotype of CX3CR1 progress to AIDS more rapidly than those with other haplotypes

ATE1 Polyclonal Antibody, 100ul Cell fragmentation and collection Chromosomal aberrations involving this geneThis gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N terminal aspartate or glutamate residues. Conjugation of arginine to the N terminal aspartate or glutamate targets proteins for ubiquitin dependent degradation. Alternative splicing results in multiple transcript variants.

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