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USF1 Polyclonal Antibody, 50ul Fluorescent Staining tumor necrosis factor (TNF)-alpha signaling

SKU: 84934660333

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USF1 Polyclonal Antibody, 50ul Fluorescent Staining tumor necrosis factor (TNF)-alpha signalingThis gene encodes a member of the basic helix loop helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine rich initiator (Inr) elements and E box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21.

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Description

tumor necrosis factor (TNF)-alpha signaling

Existence of a major autoantigenic epitope or epitopes on the C-terminal 190 amino acids of p70 containing the leucine repeat

It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor

The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein

Members in this family are of ancient origin and play an important role in organ development during embryogenesis

USF1 Polyclonal Antibody, 50ul Fluorescent Staining tumor necrosis factor (TNF)-alpha signalingThis gene encodes a member of the basic helix loop helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine rich initiator (Inr) elements and E box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21.

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