JAML1 Polyclonal Antibody, 50ul Cell Biology Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include death receptor binding

The receptor is aberrantly expressed in numerous cancers such as those of the lung

where it functions as a negative regulator of cell growth and survival

in a region thought to be associated with susceptibility for psychiatric disorders and epilepsy

angiogenesis and cell migration

JAML1 Polyclonal Antibody, 50ul Cell Biology Gene Ontology (GO) annotations relatedThe Ig like V type domain 2 mediates interaction with CXADR.,May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.,induction: Up regulated upon retinoic acid, Me2SO and PMA treatment in