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TRF1(Phospho Ser219) Polyclonal Antibody, 20ul Gene Editing The protein (ankyrin repeat domain

SKU: 84502679206

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TRF1(Phospho Ser219) Polyclonal Antibody, 20ul Gene Editing The protein (ankyrin repeat domainThis gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C terminal Myb motif, a dimerization domain near its N terminus and an acidic N terminus. Two transcripts of this gene are alternatively

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Description

The protein (ankyrin repeat domain 1) encoded by ANKRD1 is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation

This protein may function in stimulation of Ca2+-dependent insulin release| stimulation of prolactin secretion| and exocytosis

The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins

It may thus function as a specific coactivator for the mammalian TEFs

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17

TRF1(Phospho Ser219) Polyclonal Antibody, 20ul Gene Editing The protein (ankyrin repeat domainThis gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C terminal Myb motif, a dimerization domain near its N terminus and an acidic N terminus. Two transcripts of this gene are alternatively

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