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Atm (Acetyl Lys316) Rabbit Polyclonal Antibody, 20ul Recombinant Protein Pseudogenes of this gene are

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Atm (Acetyl Lys316) Rabbit Polyclonal Antibody, 20ul Recombinant Protein Pseudogenes of this gene areThe protein encoded by this gene belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus it functions as a regulator of a wide variety of downstream proteins including tumor suppressor proteins p53 and BRCA1 checkpoint kinase CHK2 checkpoint proteins RAD17 and RAD9 and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell

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Description

Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10

The protein encoded by PRKCE (protein kinase C epsilon)is one of the PKC family members

This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis

Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers

Binding of insulin or other ligands to this receptor activates the insulin signaling pathway

Atm (Acetyl Lys316) Rabbit Polyclonal Antibody, 20ul Recombinant Protein Pseudogenes of this gene areThe protein encoded by this gene belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus it functions as a regulator of a wide variety of downstream proteins including tumor suppressor proteins p53 and BRCA1 checkpoint kinase CHK2 checkpoint proteins RAD17 and RAD9 and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell

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