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IL-31R Alpha Polyclonal Antibody, 20ul Serum & Sample Tubes FTO is a nuclear protein

SKU: 84138671801

4.5
DKK97.20 DKK121.20

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IL-31R Alpha Polyclonal Antibody, 20ul Serum & Sample Tubes FTO is a nuclear proteinInterleukin 31 receptor subunit alpha encoded by IL31RA belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL 31 signaling via activation of STAT 3 and STAT 5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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Description

FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known

Hexokinases phosphorylate glucose to produce glucose-6-phosphate

The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents

The protein encoded by SLC6A11 (solute carrier family 6 member 11) is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA)

and this activity may be involved in tumor invasion

IL-31R Alpha Polyclonal Antibody, 20ul Serum & Sample Tubes FTO is a nuclear proteinInterleukin 31 receptor subunit alpha encoded by IL31RA belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL 31 signaling via activation of STAT 3 and STAT 5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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