ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome ANXA10 encodes a member (annexin

ANXA10 encodes a member (annexin A10) of the annexin family

The N-end rule pathway is one proteolytic pathway of the ubiquitin system

including regulation of cell fate and patterning during embryogenesis

which are important regulators of hematopoiesis and cardiogenesis in mammals

This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome ANXA10 encodes a member (annexinERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation