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UBA1 Polyclonal Antibody, 50ul Sealing Film This enzyme is a ubiquitously

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UBA1 Polyclonal Antibody, 50ul Sealing Film This enzyme is a ubiquitouslyUbiquitin like modifier activating enzyme 1 encoded by UBA1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X linked mouse temperature sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11. 3. Alternatively spliced transcript variants that encode the same protein have been described.

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Description

This enzyme is a ubiquitously expressed thiolester hydrolase

The alleles of this gene exhibit an unusual amount of sequence variation

Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia

which is a member of the APP (amyloid precursor protein) family including APP

Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis

UBA1 Polyclonal Antibody, 50ul Sealing Film This enzyme is a ubiquitouslyUbiquitin like modifier activating enzyme 1 encoded by UBA1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X linked mouse temperature sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11. 3. Alternatively spliced transcript variants that encode the same protein have been described.

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