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IRP-1(Phospho Ser711) Polyclonal Antibody, 20ul ADME The encoded preproprotein is proteolytically

SKU: 8348152352

4.3
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IRP-1(Phospho Ser711) Polyclonal Antibody, 20ul ADME The encoded preproprotein is proteolyticallyThe protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe 4S cluster and functions as an aconitase. Aconitases are iron sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds

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Description

The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit

Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes

and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID: 23393093)

PP2C family members are known to be negative regulators of cell stress response pathways

50 μL bottles

IRP-1(Phospho Ser711) Polyclonal Antibody, 20ul ADME The encoded preproprotein is proteolyticallyThe protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe 4S cluster and functions as an aconitase. Aconitases are iron sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds

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