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Human Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Human Genome Knockout Libraries PubMed: 15379550

SKU: 83074541853

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Human Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Human Genome Knockout Libraries PubMed: 15379550ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane (PubMed: 27144356). Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11138003, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed:

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Description

PubMed: 15379550

it undergoes a conformational change that increases its affinity for substrate proteins

where RABGAP1L inactivates RAB22A

and HDLs by hepatocytes (PubMed: 1911868

by enhancing their ligand affinity via conformational change (PubMed: 23193172)

Human Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Human Genome Knockout Libraries PubMed: 15379550ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane (PubMed: 27144356). Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11138003, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed:

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