Phospho-Akt (S473) Polyclonal Antibody, 20ul[BT-PHS00006] Peptide Modification Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to OR8J3 include G-protein coupled receptor activity and odorant binding

and a conserved C-terminal SH2 domain

The conserved helix-loop-helix ubiquitous kinase

a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein

thrombin and collagenase

Phospho-Akt (S473) Polyclonal Antibody, 20ul[BT-PHS00006] Peptide Modification Gene Ontology (GO) annotations relatedThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a